Here are a few of the things I hope to hear about:
Mac OS X (10.8) Mountain Lion - There will be several significant new features introduced to the system that I have grown to love in my iOS devices. Some of my most anticipated are Reminders, Notification Center, and AirPlay Mirroring (love this feature on iOS!!!).
Apple TV - Ben Parr writes a great post about the potential and strategy behind possible developments with the Apple TV.
iOS 6 - My iPad and iPhone have just about become my primary computing devices. They are consistently my first screens. It stands to reason that this news will be highly anticipated out of the conference.
There are several other areas that we might learn about in Apple's ecosystem. PC World does a great job of summarizing the lay of the land here. Check it out if you also need a rumor fix before the actual news starts to roll in.
I have a meeting scheduled at 10 a.m. EST today... exactly the time the Keynote begins! If you happen to be reading this and will be in that meeting too, be assured that my constant distraction with my iPad screen is just me responding to an emergency email from a client that will prevent our entire project from being jeopardized. Honestly, that's what I'm doing. ;)